Publications

Books and Conference Proceedings Volume

Imaging from cells to animals in vivo, Margarida Barroso and Xavier Intes Editors, CRC Press, in progress.

Multimodal Biomedical Imaging XII, Fred S Azar and Xavier Intes Editors, SPIE 10057, 2017.

Multimodal Biomedical Imaging XI, Fred S Azar and Xavier Intes Editors, SPIE 9701, 184 pages, 2016.

Multimodal Biomedical Imaging X, Fred S Azar and Xavier Intes Editors, SPIE 9316, 122 pages, 2015.

Multimodal Biomedical Imaging IX, Fred S Azar and Xavier Intes Editors, SPIE 8937, 202 pages, 2014.

Multimodal Biomedical Imaging VIII, Fred S Azar and Xavier Intes Editors, SPIE 8574, 152 pages, 2013.

Multimodal Biomedical Imaging VII, Fred S Azar and Xavier Intes Editors, SPIE Volume 8216, 246 pages, 2012.

Multimodal Biomedical Imaging VI, Fred S Azar and Xavier Intes Editors, SPIE Volume 7892, 222 pages, 2011.

Multimodal Biomedical Imaging V, Fred S Azar and Xavier Intes Editors, SPIE Volume 7557, 244 pages, 2010.

Multimodal Biomedical Imaging IV, Fred S Azar and Xavier Intes Editors, SPIE Volume 7171, 260 pages, 2009.

Multimodal Biomedical Imaging III, Fred S Azar and Xavier Intes Editors, SPIE Volume 6850, 224 pages, 2008.

Translational Multimodality Optical Imaging, Fred S Azar and Xavier Intes Editors, Artech House Publishing, 386 pages, 2008

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Book Chapters

1. V.K. Lee, A. Dias, M.S. Ozturk, K. Chen, B. Tricomi, D.T. Corr, X. Intes and G. Dai “3D Bioprinting and 3D Imaging for Stem Cell Engineering,” Bioprinting in Regenerative Medicine, Stem Cell Biology and Regenerative Medicine, Springer, Chapter 2, 33-66 (2015).

2. Vivek Venugopal, Qianqian Fang and Xavier Intes, “Multimodal biomedical imaging,” in Biophotonics for medical applications, Woodhead books, Chapter 1: 3-23 (2015).

3. Xavier Intes, Vivek Venugopal, Jin Chen, Fred Azar, “ Multimodal diffuse imaging system,” in Biomedical Optical Imaging Techniques: Design and Applications, Springer, Chapter 7: 351-374 (2013).

4. Xavier Intes and Fred S Azar, “ Advances in optical mammography,” in Advanced Optical Imaging Technologies for Clinical Medicine, Editors N Iftimia, W Brugge, D Hammer, Wiley &Sons, Chapter 11: 307-336 (2011).

5. Xavier Intes and Fred S Azar, “Advances in optical mammography,” in Advanced Optical Imaging Technologies for Clinical Medicine, Editors N Iftimia, W Brugge, D Hammer, Wiley &Sons, Chapter 11: 307-336 (2011).

6. Xavier Intes and Fred S Azar, “Introduction to Clinical Optical Imaging,” in Translational Multimodality Optical Imaging, Editors F. Azar and X. Intes, Chapter 1: 1-19 (2008).

7. Xavier Intes and Britton Chance, “Non-PET Functional Imaging Techniques (Part I) Optical,” in Radiologic Clinics of North America, Editor A. Alavi, PET Imaging II, 43, 221-234 (2005).

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Publications in Refereed International Journals

2017

F Yang, M Ozturk, R Yao and X Intes, “ Improving Mesoscopic Fluorescence Molecular Tomography Computational Efficiency through Data Reduction ”, Biomedical Optics Express, in review.

W. Cong, X Intes and G Wang,“ Optical Tomographic Imaging for Breast Cancer Detection ” JBO, in revisions.

F Long and X Intes, “ Dental optical tomography with UCNPs ” Journal of Biomedical Optics 22(6), 066001 (2017).

Q Pian, R Yao, N Sinsuebphon, X Intes, “ Compressive Hyperspectral Time-resolved Wide-Field Fluorescence Lifetime Imaging,” Nature Photonics,(2017).

W Han, F Long, W Cong, X Intes and Ge Wang, “ Radiative transfer with delta-Eddington-type phase functions,” Applied Mathematics and Computation 300, 70-78 (2017).

2016

M Ozturk, CW Chen, R Ji, L Zhao, BN Nguyen, J Fisher, Y Chen and X Intes, “ Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues ,” , Annals of Biomedical Engineering 44(3), 667-679 (2016).

F Long, F Li, X Intes and S Kotha, “ Efficient optical radiative transfer equation modeling by streamline diffusion modified continuous Garlekin method,” Journal of Biomedical Optics 21(3), 036003 (2016).

R Yao, X Intes and Q fang, “ Generalized Mesh-based Monte Carlo for Wide-field Sources and Detectors via Mesh Retesselation, ” Biomedical Optics Express, 7(1) 171-184 (2016).

2015

T Omer, X Intes, and J Hahn, “ Temporal data set reduction based on D-optimality for quantitative FLIM-FRET imaging. ” PLOS ONE,DOI:10.1371/journal.pone.0144421.

M Ozturk, CW Chen, R Ji, L Zhao, BN Nguyen, J Fisher, Y Chen and X Intes, “ Mesoscopic Fluorescence Molecular Tomography for Evaluating Engineered Tissues, ” Annals of Biomedical Engineering, 2015 Dec 8. [Epub ahead of print] PMID: 26645079.

Sez-Jade Chen, Nattawut Sinsuebphon, Xavier Intes. “ Assessment of Gate Width Size on Lifetime-Based Forster Resonance Energy Transfer Parameter Estimation. ” Photonics 2(4), 1027-1042 (2015).

A Edmans, X Intes.“ Mesh Optimization for Monte Carlo-based Optical Tomography.” Photonics 2, 375-391 (2015).

R Yao, P Qi and X Intes, “ Wide-Field Fluorescence Molecular Tomography with Compressive Sensing based Preconditioning,” Biomedical Optics Express 6(12), 4887-4898 (2015).

Q Pian, R Yao, L Zhao and X Intes.“ Hyperspectral time-resolved wide-field fluorescence molecular tomography based on structured light and single-pixel detection.” Optics Letters, Vol. 40, Issue 3, pp. 431-434 (2015).

F Yang, M Ozturk, L Zhao, W Cong, G Wang and X Intes, “ High-resolution mesoscopic fluorescence molecular tomography based on compressive sensing. ” IEEE Biomedical Engineering 62(1), pp. 248-255 (2015).

2014

F Long , M Ozturk , Mark Wolff , X Intes and S Kotha.“ Dental Imaging using Mesoscopic Fluorescence Molecular Tomography: An ex vivo feasibility study.” Photonics 1(4), 488-502 (2014).

S Rajoria, L Zhao, X Intes and M Barroso, “ FLIM-FRET for cancer application. ” Current Molecular Imaging,3(2), 144-161 (2014). DOI: 10.2174/2211555203666141117221111.

Q Pian, C Wang, X Chen, J Liang, L Zhao, G Wang and X Intes, “ Multimodal Biomedical Optical Imaging Review: Towards Comprehensive Investigation of Biological Tissues. ” Current Molecular Imaging,3(2), 72-87 (2014). DOI: 10.2174/2211555203666141117231651.

T Omer, L Zhao, X Intes and J Hanh, “ Reduced temporal sampling effect on accuracy of time-domain fluorescence lifetime Forster resonance energy transfer. ” Journal of Biomedical Optics 19(8), 086023 (2014).

L Zhao, H Yang, W Cong, G Wang and X Intes, “ Lp Regularization for Early Time-Gate Fluorescence Molecular Tomography. ” Optics Letters 39(14), 4156-4159 (2014).

Lingling Zhao, Ken Abe, Shilpi Rajoria, Qi Pian, Margarida Barroso, and Xavier Intes, “ Spatial light modulator based active wide-field illumination for ex vivo and in vivo quantitative NIR FRET imaging. ” Biomedical Optics Express,5(3),944-960 (2014).

Mehmet S. Ozturk, Daniel Rohrbach, Ulas Sunar, Xavier Intes, “ Mesoscopic Fluorescence Tomography of a Photosensitizer (HPPH) 3D Biodistribution in Skin Cancer. ” Academic Radiology 21(2) 2014,271-280.

2013

K Abe, L Zhao, A Periasamy, X Intes and M Barroso, “ Non-Invasive In Vivo Imaging of Near Infrared-labeled Transferrin in Breast Cancer Cells and Tumors Using Fluorescene Lifetime FRET. ” PLoS ONE 8(11): e80269. doi:10.1371/journal.pone.0080269

M Ozturk, L Zhao, V Lee, G Dai and X Intes, “ Mesoscopic fluorescence molecular tomography of reporter genes in bio printed thick tissue. ” Journal of Biomedical Optics, 18 (10), 100501 (October 03, 2013).

L Zhao, K Abe, M Barroso and X Intes, “ Active wide-field illumination for high-throughput fluorescence lifetime imaging. ” Optics Letters 38(20), 3976-3979 (2013).

X Intes,“ Guiding Light ” International Innovation , 9, 68-70 (2013).(learn more)

V Venugopal and X Intes, “Adaptive Wide-field Optical Tomography,” Journal of Biomedical Optics 18(3), 036006 (2013).

2012

V Venugopal, J Chen, M Barrosso and X Intes,“Quantitative tomographic imaging of intermolecular FRET in small animals,”Biomedical Optics Express 3(12), 3161-3175 (2012).

J Chen, Q Fang and X Intes, “Mesh-based Monte Carlo Fluorescence Molecular Tomography,” Journal of Biomedical Optics 17(10), 106009 (2012).

M Pimpalkhare, J Chen, V Venugopal and X Intes, “Ex Vivo Fluorescence Molecular Tomography of the Spine,” International Journal of Biomedical Imaging, in press (2012).

X Intes, V Venugopal, J Chen, F Azar,“ Multimodal diffuse imaging system,” in Biomedical Optical Imaging Techniques: Design and Applications, Springer, Chapter 7: 351-374 (2012).

L Zhao, V Lee, G Dai and X Intes, “ Mesoscopic Fluorescence Molecular Tomography of Tissue Engineered Vascular Construct,” Biomaterials 33 (21), 5325-5332 (2012).

V Venugopal and X Intes, “ Recent advances in optical mammography,” Current Medical Imaging Reviews 8(4), 244-259 (2012).

2011

J Chen, V Venugopal and X Intes, “ A Monte Carlo based method for fluorescence tomographic imaging with lifetime multiplexing using time gates,” Biomedical Optics Express 2, 871-886 (2011)

X Intes and Fred S Azar, “ Advances in optical mammography,” in Advanced Optical Imaging Technologies for Clinical Medicine, Editors N Iftimia, W Brugge, D Hammer, Wiley &Sons, Chapter 11: 307-336 (2011).

J Chen and X Intes,“ Comparison of Monte Carlo Methods for Fluorescence Molecular Tomography - Computational Efficiency,” Medical Physics 38 (10), 5788-5798 (2011).

2010

S Belanger, M Abran, X Intes, C Casanova and F Lesage, “Real time Diffuse Optical Tomography based on Structured Illumination,” Journal of Biomedical Optics 15, 016006 (2010)

J Chen, V Venugopal, F Lesage and X Intes, “Time Resolved Diffuse Optical Tomography with patterned light illumination and detection,” Optics Letters 35, 2121-2123 (2010)

V Venugopal, J Chen and X Intes, “Development of an optical imaging platform for functional imaging of small animals using wide-field excitation,” Biomedical Optics Express 1, 143-156 (2010)

RA Waniewski, X Intes, V Venugopal, et al., “Development of Procedures for Bioimaging Rodents using Fluorescence Molecular Tomography, Magnetic Resonance Imaging, and Microscale, Computed X-Ray Tomography,” Journal of the American Association for Laboratory Animal Science 49, 730-730 (2010)

V Venugopal, J Chen , F Lesage and X Intes, “Full-field time-resolved fluorescence tomography of small animals,” Optics Letters 35, 3189-3191 (2010)

2009

J Chen and X Intes, “Time-gated perturbation Monte Carlo for whole body functional imaging in small animals,” Optics Express 17, 19566-19579 (2009)

2008

B. Alacam, B. Yazici, X. Intes and B. Chance, “Pharmacokinetic-rate images of indocyanine green for breast tumors using near-infrared optical methods,” Phys. Med. Biol. 53, 837-859 (2008)

2007

M. Guven, E. Giladi, B. Yazici, K. Kwon and X. Intes, “Effect of discretization error and adaptive mesh generation in diffuse optical absorption imaging: Part I,” Inverse Problem 23, 1115-1133 (2007)

M. Guven, E. Giladi, B. Yazici, K. Kwon and X. Intes, “Effect of discretization error and adaptive mesh generation in diffuse optical absorption imaging: Part II,” Inverse Problems 23, 1133-1160 (2007)

2006

B. Alacam, B. Yazici, X. Intes and B. Chance, “Extended Kalman Filtering for Modeling and Analysis of ICG Pharmacokinetics in Cancerous Tumors using NIR Optical Methods,” IEEE Biomedical Engineering 53, 1861-1871 (2006).

S. Srinivasan, BW Pogue, H. Dehghani, F. Leblond and X. Intes, “Data subset algorithm for computationally efficient reconstruction of 3-D spectral imaging in diffuse optical tomography,” Optics Express 14, 5394-5410 (2006)

2005

S. Nioka, S. Wen, J. Zhang, J. Du, X. Intes, Z. Zhao, and B. Chance, “Simulation Study of Breast Tissue Hemodynamics During Pressure Perturbation,” Adv. Exp. Med. Biol. 566, 17-22 (2005).

X.Intes and B.Chance, “Non-PET Functional Imaging Techniques (Part I) Optical,” Radiologic Clinics of North America. 43, 221-234 (2005).

Y.Chen, X.Intes and B.Chance, “Development of high sensitivity near-infrared fluorescence imaging device for early cancer detection,” Biomedical Instrumentation & Technology. 39, 75-85 (2005).

S.Lam, F.Lesage and X.Intes, “Time Domain Fluorescent Diffuse Optical Tomography: Analytical expressions,” Optics Express 13, 2263-2275 (2005).

M.Guven, B.Yazici, X.Intes, and B.Chance, “Diffuse Optical Tomography with a priori Anatomical Information,” Phys. Med. Biol. 50, 2837-2858 (2005).

X. Intes, S. Djeziri, Z. Ichalalene, N. Mincu, Y. Wang, P. St-Jean F. Lesage, D. Hall, D. Boas, M. Polyzos, D. Fleiszer & B Mesurolle, “Time-Domain Optical Mammography SoftScan: Initial Results,“ Academic Radiology 12, 934-947 (2005).

X. Intes and B. Chance, “Multi-frequency Diffuse Optical Tomography,” Journal of Modern Optics 52, 2139-2159 (2005).

2004

X.Intes, C.Maloux, M.Guven, B.Yazici and B.Chance, “Diffuse Optical Tomography with physiological and spatial a-priori constraints,” Phys. Med. Biol. 49, N155-164 (2004).

G Zheng, Y Chen, X Intes, B Chance and J Glickson, “Contrast-Enhanced NIR Optical Imaging for subsurface cancer detection,” Journal of Porphyrin and Phthalocyanines 8, 1106- 1118 (2004).

2003

Y.Chen, X.Intes, D.R.Tailor, R.Regatte, H.Ma, V.Ntziachristos, J.Leigh, R.Reddy and B.Chance, “Probing Rat Brain Oxygenation with Near-Infrared (NIR) Spectroscopy and Magnetic Resonance Imaging (MRI),” Oxygen Transport to Tissue XXIII, edited by D.Wilson et al., Kluwer academic, 199-204 (2003).

Y.Chen, D.Tailor, X.Intes and B.Chance, “Correlation between Near-Infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI) on rat brain oxygenation modulation,” Phys. Med. Biol. 48, 417-427 (2003).

X.Intes, J.Ripoll, T.Kitai, Y.Chen, S.Nioka, A.Yodh and B.Chance, “In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green,” Medical Physics 30, 1039-1047 (2003).

Y.Chen, C.Mu, X.Intes, D.Blessington and B.Chance, “Near-infrared phase cancellation instrument for fast and accurate localization of fluorescent heterogeneity,” Rev. Sci. Instrum. 74, 3466-3473 (2003).

Y. Chen, G. Zheng, Z. Zhang, D. Blessington, M. Zhang, H. Li, Q. Liu, L. Zhou, X. Intes and B. Chance, “Metabolism Enhanced Tumor Localization by Fluorescence Imaging: In Vivo Animal Studies,” Optics Letters 28, 2070-2072 (2003).

2002

X.Intes, V.Ntziachristos, J.Culver, A.Yodh and B.Chance, “Projection access order in Algebraic Reconstruction Techniques for Diffuse Optical Tomography,” Phys. Med. Biol. 47, N1-N10 (2002).

X.Intes, V.Ntziachristos and B.Chance, “Analytical model for dual-interfering sources Diffuse Optical Tomography,” Optics Express 10, 2-14 (2002).

X.Intes, Y.Chen, X.Li and B.Chance, “Detection limit enhancement of fluorescent heterogeneities in turbid media by dual-interfering excitation,” Applied Optics 41, 3999-4007 (2002).

Y.Lin, G.Lech, S.Nioka, X.Intes and B.Chance, “Non-invasive, low-noise, fast imaging of blood volume and deoxygenation changes in muscles using LED continuous-wave (CW) imager,” Review of Scientific Instruments 73, 3065-74 (2002).

T.Tu, Y.Chen, J.Zhang, X.Intes and B.Chance, “Analysis on Performance and Optimization of Frequency-domain Near-Infrared Instruments,” J. Biomed. Opt. 7, 643-649 (2002).

Y.Chen, C.Mu, X.Intes and B.Chance, “Adaptive Calibration for Object Localization in Turbid Media with Interfering Diffuse Photon Density Waves,” Applied Optics 41, 7325-7333 (2002).

2001

X.Intes, B.Chance, M.Holboke and A.Yodh, “Interfering diffusive photon-density waves with an absorbing-fluorescent inhomogeneity,” Optics Express 8, 223-231 (2001).

Y.Chen, C.Mu, X.Intes and B.Chance, “Signal-to-noise analysis for detection sensitivity of small absorbing heterogeneity in turbid media with single-source and dual-interfering-source,” Optics Express 9, (2001).

2000

F.Pellen, X.Intes, P.Olivard, Y.Guern, J.Cariou and J.Lotrian, “Determination of water frequency response by backscattering measurement,” J. Phys. D: Appl. Phys. 33, 349-354 (2000).

1999

X.Intes, B.Le Jeune, F.Pellen, Y.Guern, J.Cariou and J.Lotrian, “Localization of the virtual point source used in the diffusion approximation to model collimated beam source,” Waves in Random Media 9, 489-499 (1999).

1997

X.Intes, B.Le Jeune, F.Pellen, Y.Guern, J.Cariou and J.Lotrian, “Determination of optical properties of multiple-scattering media by using a coherent-modulated source,” J. Opt. 28, 218-224 (1997).

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Peer reviewed full-length abstracts (INSPEC/ Web of knowledge accessed 10/2011)

2016

99. Chen, S.-J.; Sinsuebphon, N.; Barroso, M.; Intes, X.; Michalet, X., “ AlliGator: A Phasor Computational Platform for Fast in vivo Lifetime Analysis, ” Optical Molecular Probes, Imaging and Drug Delivery, Paper# OmTu2D.2, 2017.

98. Yao, R.; Intes, X.; Fang, Q., “ A Rapid Approach to Build Jacobians for Optical Tomography via Monte Carlo Method and Photon “ Replay ” , ” Bio-Optics: Design and Application, Paper# BoW3A.3, 2017.

97. Nemani, A.; Kruger, U.; Intes, X.; De, S., “ Increased Sensitivity in Discriminating Surgical Motor Skills Using Prefrontal Cortex Activation over Established Metrics,” Bio-Optics: Design and Application, Paper# JTu4A.11, 2017.

96. Rudkouskaya, A.; Sinsuebphon, N.; Intes, X.; Barroso, M., “ Fluorescence lifetime FRET non-invasive imaging of breast cancer xenografts provides a measure of target engagement in vivo, ” Proceedings of the SPIE - Progress in Biomedical Optics and Imaging, v 10049, p 1004908 (1 pp.), 2017.

95. G Wang, W Cong, Q Yang, Q Pian, S Zhu, J Liang, M Barroso and X Intes,“ Innovation and fusion of x-ray and optical tomography for mouse studies of breast cancer, ” Proc. SPIE 9967, Developments in X-Ray Tomography X, 99671R, 2016.

94. R Yao, X Intes, Q Fang,“ Enabling wide-field illumination and detection in mesh-based Monte Carlo simulations,” Biomedical Optics 2016 OSA Technical Digest OW4D. 5, 2016.

93. MS Ozturk, VK Lee, G Dai, X Intes,“ Longitudinal Volumetric Assessment of Glioblastoma Brain Tumor in 3D Bio-Printed Environment by Mesoscopic Fluorescence Molecular Tomography,” Biomedical Optics 2016 OSA Technical Digest JM3A. 46, 2016.

92. N Sinsuebphon, A Rudkouskaya, M Barroso, X Intes,“ Whole body lifetime FRET imaging in transmission and reflectance for the assessment of drug delivery efficacy in small animals,,” Biomedical Optics 2016 OSA Technical Digest JM3A. 48, 2016.

91. Q Pian, R Yao, N Sinsuebphon, X Intes,“ Hyperspectral Compressive Single-Pixel Imager for Fluorescence Lifetime Sensing,” Biomedical Optics 2016 OSA Technical Digest OTu2C. 7, 2016.

90. A Rudkouskaya, N Sinsuebphon, X Intes, M Barroso,“ Role of Tumor Heterogeneity in Imaging Breast Cancer Targeted Delivery using FLIM FRET in Vivo,,” Biomedical Optics 2016 OSA Technical Digest CTh2A. 5, 2016.

89. SJ Chen, N Sinsuebphon, A Rudkouskaya, M Barroso, X Intes,“ Fluorescence Lifetime-based Multiplexing of Near-Infrared Forster Resonance Energy Transfer Pairs,” Biomedical Optics 2016 OSA Technical Digest, JW3A.36, 2016.

88. Long, F.; Intes, X.; Kotha, S.,“ Dental Optical Tomography with UCNPs,” Biomedical Optics 2016 OSA Technical Digest, JW3A.3, 2016.

87. Yao, R.; Zhao, L.; Intes, X.,“ Sparse temporal sampling for fast time-domain wide-field fluorescence molecular tomography,” Proceedings Volume 9701: Multimodal Biomedical Imaging XI, 2016.

86. Sez-Jade Chen, SJ.; Intes, X. ,“ Gate-width impact on NIR FRET lifetime fitting using gated ICCD,” Proceedings Volume 9701: Multimodal Biomedical Imaging XI, 2016.

85. Sinsuebphon, N.; Rudkouskaya, A.; Barroso, M.; Intes, X. ,“ Wide-field lifetime-based FRET imaging for the assessment of early functional distribution of transferrin-based delivery in breast tumor-bearing small animals,” Proceedings Volume 9689: Photonic Therapeutics and Diagnostics XII, 2016.

84. Pian, Q.; Yao, R.; Intes, X. ,“ Time-resolved hyperspectral single-pixel camera implementation for compressive wide-field fluorescence lifetime imaging,” SPIE Proceedings Volume 9701: Multimodal Biomedical Imaging XI, 2016.

2015

83. Intes, X. ,“ Wide-field lifetime-based Forster Resonance Energy Transfer in Live animals,” Conference on Lasers and Electro-Optics (CLEO). Proceedings, p 2 pp., 2015.

82. Omer, T.; Intes, X.; Hahn, J. “ Sensitivity analysis-based time gate selection procedure for biexponential fluorescence imaging,” 41st Annual Northeast Biomedical Engineering Conference (NEBEC). Proceedings, p 1-2, 2015

81. Yao, R.; Intes, X.; Fang Q. “ Re-tessellated mesh-based Monte Carlo for wide-field illumination sources,” 41st Annual Northeast Biomedical Engineering Conference (NEBEC). Proceedings, p 1-2, 2015

80. Tricomi, B.J.; Ozturk, M.S.; Intes, X.; Corr, D.T., “ Biofabrication and 3D localization of multilayered cellular constructs using Laser Direct-Write and Mesoscopic Fluorescent Molecular Tomography, ” 41st Annual Northeast Biomedical Engineering Conference (NEBEC). Proceedings, p 1-2, 2015

79. Pian Q.; Yao R.; Intes, X. “ Multispectral time-resolved diffuse optical tomography system for absorber mapping in turbid medium using wide-field single-pixel camera,” 41st Annual Northeast Biomedical Engineering Conference (NEBEC).

Proceedings, p 1-2, 2015

78. Nemani, A.; Intes, X.; De, S. “ Surgical motor skill differentiation via functional near infrared spectroscopy,” 41st Annual Northeast Biomedical Engineering Conference (NEBEC). Proceedings, p 1-2, 2015

77. Sez-Jade Chen and Intes, X. “ Assessment of gate width size on lifetime-based Forster Resonance Energy Transfer parameter estimation,” 41st Annual Northeast Biomedical Engineering Conference (NEBEC). Proceedings, p 1-2, 2015

76. Ji, R.; Ozturk, M.S.; Intes, X. “ SNR characterization of mesoscopic fluorescence molecular tomography with EMCCD camera,” 41st Annual Northeast Biomedical Engineering Conference (NEBEC). Proceedings, p 1-2, 2015

75. Intes, X. “ Wide-field lifetime-based Forster Resonance Energy Transfer in Live animals,” Conference on Lasers and Electro-Optics (CLEO). Proceedings, p 2 pp., 2015

2014

74. Edmans, A., Smith, Cameron, Intes, X. “ Solution field metrics in mesh optimization for Monte Carlo based optical tomography,” Biomedical Optics (BIOMED) 2014 paper: BM3A.40

73. Nemani, A.; Intes, X.; De, S., “ Monte Carlo Based Simulation of Sensitivity Curvature for Evaluating Optimal Probe Geometry,” Biomedical Optics (BIOMED) 2014 paper: BM3A.36

72. Pian, Q.; Zhao, L.; Yao, R.; Intes, X., “ Time-resolved Hyperspectral Diffuse Optical Tomography: proof of concept,” Biomedical Optics (BIOMED) 2014 paper: BM3A.35

71. Ozturk, M.; Intes, X., “ Photodynamic Therapy Agent Bio-distribution in 3D with Mesoscopic Fluorescence Molecular Tomography,” Biomedical Optics (BIOMED) 2014 paper: BM3A.38

70. Zhao, L.; Yang, H.; Cong, W.; Wang, G.; Intes, X., “ Compressive Sensing for Early Time-gate Reconstruction in Time-domain Fluorescence Molecular Tomography,” Biomedical Optics (BIOMED) 2014 paper: BM3A.37

69. Sinsuebphon, N.; Bevington, T.; Zhao, L.; Ken, A.; Barroso, M.; Intes, X., “ Comparison of Near-Infrared Fluorophore Pairs for Lifetime-Based FRET Imaging,” Biomedical Optics (BIOMED) 2014 paper: BM3A.39

68. Yang, F.; Intes, X., “ High Resolution Fluorescence Laminar Optical Tomography Based on lp-Norm Regularization,” Biomedical Optics (BIOMED) 2014 paper: BM3A.41

67. Zhao, L.; Rajoria, S.; Barroso, M.; Intes, X., “ Active Wide-field Illumination For In Vitro, Ex Vivo and In Vivo NIR FRET Imaging,” Biomedical Optics (BIOMED) 2014 paper: BW3B.5

66. Yang F.; Ozturk, M.S.; Cong W.; Wang G.; Intes, X., “ High resolution 3D image reconstruction in laminar optical tomography based on compressive sensing,” Proceedings of the SPIE - Progress in Biomedical Optics and Imaging, v 8937, p 89370R (5 pp.), (2014).

65. Sinsuebphon, N.; Bevington, T.; Lingling Zhao; Ken, A.; Barroso, M.; Intes, X. “ Comparison of NIR FRET pairs for quantitative transferrin-based assay,” Proceedings of the SPIE - Progress in Biomedical Optics and Imaging, v 8937, p 89370X (7 pp.), (2014).

64. Zhao L.; Yang H.; Cong W.; Wang G.; Intes, X. “ Comparison of lp-regularization-based reconstruction methods for time domain fluorescence molecular tomography on early time gates,” Proceedings of the SPIE - Progress in Biomedical Optics and Imaging, v 8937, p 89370V (6 pp.), (2014).

63. Pian Q.; Intes, X. “ Structured light based hyperspectral time-resolved diffuse optical tomography system Source,” Proceedings of the SPIE - Progress in Biomedical Optics and Imaging, v 8937, p 89370T (6 pp.), (2014).

62. Edmans, A.; Smith, C.; Intes, X. “ Mesh optimization for fluorescence molecular tomography,” Proceedings of the SPIE - Progress in Biomedical Optics and Imaging, v 8937, p 89370S (7 pp.), (2014).

61. Long F.; Ozturk, M.S.; Intes, X.; Kotha, S. “ Dental imaging using laminar optical tomography and micro CT, ” Proceedings of the SPIE - Progress in Biomedical Optics and Imaging, v 8937, p 89370P (6 pp.), (2014).

2013

60. Hyman, A.; Zhao, L.; Intes, X. “ Multi-modal Imaging Cassette for Small Animal Molecular Imaging,” 9th Annual Northeast Bioengineering Conference (NEBEC 2013), p 167-8 (2013).

59. Ozturk, M.S.; Lee, V.K.; Zhao L.; Guohao Dai; Intes, X. “ Laminar Optical Tomography Applied to Reporter Genes Imaging in Engineered Tissue Constructs,” 39th Annual Northeast Bioengineering Conference (NEBEC 2013), p 129-30 (2013).

58. Zhao, L.; Abe, K.; Barroso, M.; Intes, X. “ Enhanced dynamic range and accuracy of fluorescence lifetime imaging by active illumination, ” 39th Annual Northeast Bioengineering Conference (NEBEC 2013), p 151-2 (2013).

57. Pian, Q.; Zhao, L.; Intes, X. “ Time-Resolved Multispectral Diffuse Optical Tomography System Based on Structured Illumination and Detection,” 39th Annual Northeast Bioengineering Conference (NEBEC 2013), p 169-70 (2013).

56. Zhao, L.; Abe, K.; Barroso, M.; Intes, X. “ In vivo time-resolved fluorescence imaging of a NIR FRET probe in live mice,” 39th Annual Northeast Bioengineering Conference (NEBEC 2013), p 133-4 (2013).

55. Omer, T.; Sinsuebphon, N.; Intes, X.; Hahn, J. “ Selection of Temporal Gates for Bi-Exponential Fluorescence Lifetime Imaging,” 39th Annual Northeast Bioengineering Conference (NEBEC 2013), p 11-12 (2013).

54. Venugopal, V.; Jin Chen; Intes, X. “ Robust imaging strategies in time-resolved optical tomography,” SPIE, v 8578, p 857827 (8 pp.) (2013).

2011

53. Chen, J.; Intes, X, “Mesh-based Monte Carlo method for time-gated optical tomography,” 37th Annual Northeast Bioengineering Conference, p 2 pp., (2011).

52. Venugopal, V.; Chen, J.; Barroso, M; Intes, X, “In vivo reconstruction of NIR FRET using full-field time resolved optical tomography,” 37th Annual Northeast Bioengineering Conference, p 2 pp. (2011).

51. Nesbitt, R.S.; Macione, J.J.; Wentzell, S.; Corr, D.T.; Intes, X.; Kotha, S.P., “Mapping of Strains In Bundles Of Skin Collagen Microfibrils,” 37th Annual Northeast Bioengineering Conference, p 2 pp., (2011).

50. Zhao, L.; Lee, V.; Dai, G.; Intes, X., “Mesoscopic fluorescence molecular imaging of tissue engineered vascular construct,” 37th Annual Northeast Bioengineering Conference, p 2 pp., (2011).

49. Venugopal, V.; Chen, J.; Intes, X., “Adaptive correction of dynamic range in small animal wide-field fluorescence tomography,” 37th Annual Northeast Bioengineering Conference, p 2 pp., (2011).

48. Pimpalkhare, M.; Venugopal, V.; Chen, J.; Intes, X., “Anatomical segmentation for guided Fluorescence Molecular Tomography in small animals,” 37th Annual Northeast Bioengineering Conference, p 2 pp., (2011).

2010

47. Venugopal, V.; Chen J; Intes, X., “On the use of wide-field light patterns for small animal optical molecular imaging,” 36th Annual Northeast Bioengineering Conference, p 2 pp., (2010)

46. Chen J; Venugopal, V.; Intes, X., “Time gated optical imaging for functional and structural imaging,” 36th Annual Northeast Bioengineering Conference, p 2 pp., (2010)

2009

45. Venugopal, V.; Jin Chen; Intes, X., “Quantifying optical properties in small animals using MR-guided multispectral time-resolved imaging, “Proceedings of the SPIE Vol 7171, 717114 (8 pp.) (2009)

44. Tasimi, K.; Intes, X.; Roysam, B., “Unmixing multiple markers with spectral lifetime measurements,” Proceedings of the SPIE Vol 7171, p 717112 (7 pp.) (2009)

43. Chen J; Venugopal, V.; Intes, X., “Diffuse optical tomography with time-gated perturbation Monte Carlo method,” Proceedings of the SPIE Vol 7171, p 717113 (9 pp.) (2009)

2007

42. Guven, M; Yazici, B; Giladi, E; Intes, X, “Adaptive mesh generation for diffuse optical tomography,” 4th IEEE International Symposium on Biomedical Imaging - Macro to Nano Vols 1-3: 1380-1383 (2007)

41. Sunar, U; Ghoroghchian, PP; Intes, X; Therien, MJ; Hammer, DA; Yodh, AG, “Pharmacokinetic assessment of a polymersome-based molecular beacon by in vivo fluorescence monitoring,” Proceedings of the SPIE - Optical Tomography and Spectroscopy of Tissue VII, 6434: I4342-I4342 (2007)

2006

40. Alacam, B; Yazici, B; Intes, X; Nioka, S; Chance, B, “Spatially resolved pharmacokinetic rate images of ICG using near infrared optical methods,” Proceedings of the SPIE - Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IV, 6088: N881-N881 (2006)

39. Busch, DR; Zhao, ZY; Nioka, S; Yodh, AG; Schnall, M; Chance, B; Intes, X, “Fast CW imager for ICG and Gd kinetics,” Proceedings of the SPIE - Multimodal Biomedical Imaging, 6081: R810-R810 (2006)

38. Guven, M; Yazici, B; Intes, X; Chance, B, “Hierarchical Bayesian algorithm for diffuse optical tomography,” 34th Applied Imagery and Pattern Recognition Workshop-MultiModal Imaging 140-145 (2006)

37. Alacam, B.; Yazici, B.; Serdaroglu, A.; Intes, X.; Chance, B.; Nioka, S., “Reconstruction of spatially resolved pharmacokinetic rate images of fluorescence agents in FDOT,” Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society p 4 pp. (2006)

36. Guven, M; Yazici, B; Kwon, K; Giladi, E; Intes, X, “Discretization error based mesh generation for diffuse optical tomography,” 34th Applied Imagery and Pattern Recognition Workshop – MultiModal Imaging 146-151 (2006)

2005

35. Nioka, S; Wen, S; Zhang, J; Du, J; Intes, X; Zhao, ZY; Chance, B, “Simulation study of breast tissue hemodynamics during pressure perturbation,” 31st Annual Meeting of the International-Society-on-Oxygen-Transport-to-Tissue 566: 17-22 (2005)

34. Alacam, B; Yazici, B; Intes, X; Chance, B, “Extended kalman filtering for the modeling and analysis of ICG pharmacokinetics using NIR optical methods,” Proceedings of the SPIE-Optical Tomography and Spectroscopy of Tissue VI, 5693: 17-27 (2005)

33. Alacam, B; Yazici, B; Intes, X; Chance, B, “Analysis of ICG pharmacokinetics in cancerous tumors using NIR optical methods,” 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vols 1-7: 62-65 (2005)

2004

32. Chen, Y; Zheng, G; Zhang, ZH; Blessington, D; Intes, X; Achilefu, S; Chance, B, “Imaging of tumor hyper-metabolism with near-infrared fluorescence contrast agents,” Proceedings of the SPIE-Optical Technologies in Biophysics and Medicine V 5474: 147-153 (2004)

31. Son, IY; Guven, M; Yazici, B; Intes, X, “A 2-level domain decomposition algorithm for inverse diffuse optical tomography,” International Conference on Image Processing (ICIP), Vols 1- 5: 3315-3318 (2004)

30. Intes, X; Djeziri, S; Ichalalene, Z; Mincu, N; Wang, Y, “Time-domain optical mammography softscan (R) : Initial results on detection and characterization of breast tumors,” Proceedings of the SPIE-Photonics North 5578: 188-197 Part 1-2 (2004)

29. Lam, S; Lesage, F; Intes, X, “Time domain fluorescent diffuse optical tomography,” Proceedings of the SPIE-Photonics North 5578: 179-187 Part 1-2 (2004)

2003

28. Zhang, J; Tu, T; Sunar, U; Intes, X; Nioka, S; Zhang, ZH; Kilger, A; Lustig, R; Loevner, L; Chance, B, “Application of I&Q Detection system in scouting the curative effect of neck squamous cell carcinoma,” Proceedings of the SPIE-Optical Tomography and Spectrosopy of Tissue V 4955: 575-580 (2003)

27. Guven, M; Yazici, B; Intes, X; Chance, B, “Diffuse optical tomography with a priori anatomical information,” Proceedings of the SPIE-Optical Tomography and Spectrosopy of Tissue V 4955: 634-646 (2003)

26. Guven, M; Yazici, B; Intes, X; Chance, B, “Three-dimensional diffuse optical tomography with a priori anatomical information,” Proceedings of the SPIE-Photon Migration and Diffuse-Light Imaging 5138: 268-280 (2003)

25. Huang, P; Intes, X; Chance, B; Nioka, S, “Simulation of delivery of indocynanine green injected intravenously into the human subject for breast cancer detection,” Proceedings of the SPIE-Lasers in Surgery-Advanced Characterization, Therapeutics and Systems XIII 4949: 450-459 (2003)

24. Guven, M; Yazici, B; Intes, X; Chance, B, “An adaptive V-grid algorithm for diffuse optical tomography,” IEEE 29th Annual Northeast Bioengineering Conference 95-97 (2003)

23. Guven, M; Yazici, B; Intes, X; Chance, B, “An adaptive multigrid algorithm for region of interest diffuse optical tomography,” IEEE International Conference on Image Processing Vol 2, 823-826 (2003)

22. Chen, Y; Blessington, D; Zhang, ZH; Liu, Q; Zhou, LL; Mu, CP; Intes, X; Achilefu, S; Li, H; Zhang, M; Zheng, G; Chance, B, “Determination of subsurface tumor localization in animal models with near-infrared (NIR) fluorescence imaging,” Proceedings of the SPIE-Optical Tomography and Spectrosopy of Tissue V 4955: 322-329 (2003)

21. Chen, Y; Intes, X; Tailor, DR; Regatte, RR; Ma, H; Ntziachristos, V; Leigh, JS; Reddy, R; Chance, B, “Probing rat brain oxygenation with near-infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI),” 29th Annual General Meeting of the International-Society-for-Oxygen-Transport-to-Tissue 510: 199-204 (2003)

20. Chen, Y; Liu, Q; Huang, P; Hyman, S; Intes, X; Lee, W; Chance, B, “Assessment of tumor angiogenesis using fluorescence contrast agents,” Proceedings of the SPIE-3rd International Conference on Photonics and Imaging in Biology and Medicine 5254: 296-301 (2003)

2002

19. Intes, X; Yu, JS; Yodh, AG; Chance, B, “Development and evaluation of a multi wavelength multi-channel time resolved optical instrument for NIR/MRI mammography co-registration,” : IEEE 28th Annual Northeast Bioengineering Conference 91-92 (2002)

18. Chen, Y; Mu, CP; Intes, X; Chance, B, “Diffuse optical tomography using dual-interfering-source,” Proceedings of the SPIE-International Workshop on Photonics and Imaging in Biology and Medicine 3 (26): 253-260 (2002)

17. Guven, M; Yazici, B; Intes, X; Chance, B; Zheng, Y, “Recursive least squares algorithm for optical diffusion tomography,” IEEE 28th Annual Northeast Bioengineering Conference 273-274 (2002)

16. Mu, CP; Chen, Y; Intes, X; Chance, B; Luo, QM, “Electro-optical scanning null-line improving detection sensitivity of phased array system,” IEEE 28th Annual Northeast Bioengineering Conference 75-76 (2002)

15. Chen, Y; Mu, CP; Intes, X; Nioka, S; Chance, B, “Fast imaging of fluorescence labeled tumor,” IEEE 28th Annual Northeast Bioengineering Conference 77-78 (2002)

14. Intes, X; Ripoll, J; Chen, Y; Nioka, S; Yodh, AG; Chance, B, “Diffuse optical tomography of breast with non-specific contrast agent,” IEEE 28th Annual Northeast Bioengineering Conference 87-88 (2002)

13. Yu, JS; Intes, X; Luo, QM; Chance, B, “Recovery of optical parameters in diffusive media with gated-photon counting,” IEEE 28th Annual Northeast Bioengineering Conference 89-90 (2002)

12. Intes, X; Ntziachristos, V; Yodh, A; Chance, B, “Combining various projection access schemes with the algebraic reconstruction technique for Diffuse Optical Tomography,” Proceedings of the SPIE - International Workshop on Photonics and Imaging in Biology and Medicine 3 (26): 108-118 (2002)

11. Huang, P; Intes, X; Nioka, S; Kitai, T; Chance, B, “Method and application for imaging of breast cancer using a contrast agent,” Proceedings of the SPIE - International Workshop on Photonics and Imaging in Biology and Medicine 3 (26): 194-202 (2002)

10. Chen, Y; Zhou, LL; Mu, CP; Intes, X; Achilefu, S; Chance, B, “Phase cancellation system for tumor imaging using targeted fluorescent contrast agents,” Proceedings of the SPIE-Photonics Asia Symposium 4916: 22-29 (2002)

9. Yu, C; Mu, C; Intes, X; Chance, B; “Adaptive calibration for object localization in turbid media with interfering diffuse photon density waves,” Proceedings of the SPIE,4916: 22-29 (2002)

8. Chance, B; Chen, Y; Intes, X; Zhang, J; Glickson, J; Blessington, D; Zhou, L; Zheng, G; Lu, P; Achilefu, S; Tung, C, “Breast cancer detection by phased array localization of fluorescent molecular beacons,” Proceedings of the SPIE-Optical Technologies in Biophysics and Medicine IV 5068: 493-509 (2002)

2001

7. Chen, Y; Intes, X; Zhou, SM; Mu, CP; Holboke, M; Yodh, AG; Chance, B, “Detection sensitivity and optimization of phased array system,” Proceedings of the SPIE - Optical Tomography and Spectroscopy of Tissue IV 2 (7): 211-218 (2001)

6. Intes, X; Ntziachristos, V; Yodh, AG; Chance, B, “Imaging with dual-interfering sources,” Proceedings of the SPIE-Optical Tomography and Spectroscopy of Tissue IV 2 (7): 68-75 (2001)

5. Intes, X; Chen, Y; Li, XD; Chance, B, “Fluorescent heterogeneities in turbid media: Limits for detection with dual-interfering sources excitation,” 23rd Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society 23: 3139-3142 Part 1-4 (2001)

2000

4. Intes, X; Kang, KA; Holboke, M; Yodh, A; Chance, B, “Dual-interfering sources with a fluorescent object,” Proceedings of the SPIE-Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography 1 (31): 140-142 (2000)

3. Intes, X; Ntziachristos, V; Holboke, M; Yodh, A; Chance, B, “On the spatial resolution of diffuse optical tomography,” Biomedical Topical Meeting, Technical Digest, 38: 481-483 (2000)

1999

2. Intes, X; Le Jeune, B; Pellen, F; Guern, Y; Cariou, J; Lotrian, J, “Localisation of the virtual point source used in the diffusion approximation to model collimated beam source,” Proceedings of the SPIE-Optical Tomography and Spectroscopy of Tissue III 3597: 183-199 (1999)

1998

1. Pellen, F; Intes, X; Guern, Y; Cariou, J; Lotrian, J, “Picosecond optical pulse backscattering measurement: Determination of ocean water transfer function,” IEEE OCEANS Conference and Exhibition on Engineering for Sustainable Use of the Oceans (OCEANS 98) Vols 1-3: 1436-1438 (1998)

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Student dissertations

Phd Dissertations

Mehmet Saadeddin Ozturk, HIGH-RESOLUTION AND HIGH SENSITIVITY MESOSCOPIC FLUORESCENCE TOMOGRAPHY BASED ON DE-SCANNING EMCCD: SYSTEM DESIGN AND THICK TISSUE IMAGING APPLICATIONS (Dec 2016).

Feixiao Long, Optical tomography and light irradiation to reduce bacterial loads in oral health application (May 2016).

Lingling Zhao, IN VIVO NEAR-INFRARED FORSTER RESONANCE ENERGY TRANSFER SMALL ANIMAL IMAGING (May 2015).

Jin Chen, OPTICAL TOMOGRAPHY IN SMALL ANIMALS WITH TIME-RESOLVED MONTE CARLO METHODS (August 2012).

Vivek Venugopal, A SMALL ANIMAL TIME-RESOLVED OPTICAL TOMOGRAPHY PLATFORM USING WIDE-FIELD EXCITATION (November 2011).

Master Dissertations

Andrew Edmans,MESH OPTIMIZATION FOR MONTE CARLO BASED OPTICAL TOMOGRAPHY (April 2014).

Monish Sanat Pimpalkhare,EX-VIVO MOLECULAR OPTICAL IMAGING OF THE SPINE (January 2012).

Krenar Tasimi,SPECTRAL-LIFETIME UNMIXING ALGORITHMS FOR BIOLOGICAL FLUORESCENCE IMAGING (July 2009).

Vivek Venugopal,DEVELOPMENT OF IMAGING PLATFORM FOR MULTI-SPECTRAL BIOLUMINESCENCE IMAGING (November 2007).

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